甘油-3-磷酸脱氢酶 [NAD(P)+]

甘油-3-磷酸脱氢酶 [NAD(P)⁺]（英語：glycerol-3-phosphate dehydrogenase [NAD(P)⁺]，EC 1.1.1.94 （页面存档备份，存于互联网档案馆）），是一种以NAD⁺或NADP⁺为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下酶促反应：

甘油-3-磷酸脱氢酶 [NAD(P)+]
命名 系统命名 sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase 缩写 别名 L-glycerol-3-phosphate:NAD(P) oxidoreductase; glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate)); glycerol 3-phosphate dehydrogenase (NADP); glycerol-3-phosphate dehydrogenase [NAD(P)]
识别码
EC編號	1.1.1.94
CAS号	37250-30-9
数据库
IntEnz	IntEnz浏览
BRENDA	BRENDA入口
ExPASy	NiceZyme浏览
KEGG	KEGG入口
MetaCyc	代谢路径
PRIAM	概述
PDB	RCSB PDB PDBj PDBe PDBsum
基因本体	AmiGO / EGO
搜索 PMC 相关文献 PubMed 相关文献

sn-甘油-3-磷酸 + NAD(P)⁺ $\rightleftharpoons$ 磷酸甘油酮 + NAD(P)H + H⁺

甘油-3-磷酸脱氢酶 [NAD(P)⁺]主要参与磷酸甘油酯的代谢过程。大肠杆菌（Escherichia coli）的甘油-3-磷酸脱氢酶 [NAD(P)⁺]显示出对NADPH的B域的特异性。

参考文献

• Kito M, Pizer LI. Purification and regulatory properties of the biosynthetic L-glycerol 3-phosphate dehydrogenase from Escherichia coli. J. Biol. Chem. 1969, 244 (12): 3316–3323. PMID 4389388. 
• Edgar JR, Bell RM. Biosynthesis in Escherichia coli fo sn-glycerol 3-phosphate, a precursor of phospholipid. J. Biol. Chem. 1978, 253 (18): 6348–6353. PMID 355254. 
• Edgar JR, Bell RM. Biosynthesis in Escherichia coli of sn-glycerol 3-phosphate, a precursor of phospholipid. Kinetic characterization of wild type and feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate dehydrogenase. J. Biol. Chem. 1978, 253 (18): 6354–6363. PMID 28326. 
• Edgar JR, Bell RM. Biosynthesis in Escherichia coli of sn-glycerol-3-phosphate, a precursor of phospholipid. Further kinetic characterization of wild type and feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate dehydrogenase. J. Biol. Chem. 1980, 255 (8): 3492–3497. PMID 6767719.