癸酰氯
化合物
癸酰氯是一种有机化合物，化学式为C10H19ClO。它可由1-癸酸和氯化亚砜（或草酰氯[5]）回流反应制得。[6]它可以被Zn(BH4)2–TMEDA在乙醚中还原为1-癸醇。[7]在吡啶的存在下，它和苯胺在二氯甲烷中反应，可以得到N-苯基癸酰胺。[8]
| 癸酰氯 | |
|---|---|
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| 识别 | |
| CAS号 | 112-13-0 
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| SMILES |
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| 性质 | |
| 化学式 | C10H19ClO |
| 摩尔质量 | 190.71 g·mol−1 |
| 密度 | 0.943±0.06 g·cm−3（20 °C）[1] |
| 熔点 | −34.5 °C（238.7 K）[2] |
| 沸点 | 115—116 °C（388—389 K）（5 torr）[3] 116 °C（389 K）（18 torr）[4] |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
参考文献 编辑
- ^ Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 ((C) 1994-2021 ACD/Labs). Retrieved from SciFindern. [2021-01-26].
- ^ "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFindern. [2021-01-26].
- ^ Toriyama, Masaharu; Kamijo, Haruo; Motohashi, Shigeyasu; Takido, Toshio; Itabashi, Kunio. A Facile Synthesis of Thioacids by Hydrolysis of 1-(Acylthio)ethaniminium Chlorides. Phosphorus, Sulfur, and Silicon and the Related Elements. 2010, 178 (8): 1661–1665. ISSN 1042-6507. doi:10.1080/10426500307837.
- ^ Cainelli, Gianfranco; Contento, Michele; Manescalchi, Francesco; Plessi, Laura. Polymer-Bonded Lewis Acids in Organic Synthesis: Conversion of Carboxylic Acids into Acyl Chlorides and of Alcohols into Alkyl Chlorides or Bromides by Polymer-Bonded Phosphorus Reagents. Synthesis. 1983, 1983 (04): 306–308. ISSN 0039-7881. doi:10.1055/s-1983-30314.
- ^ Srikanth Vudhgiri, Dhevendar Koude, Dileep Kumar Veeragoni, Sunil Misra, R.B.N. Prasad, Ram Chandra Reddy Jala. Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides. Bioorganic & Medicinal Chemistry Letters. 2017-08, 27 (15): 3370–3373 [2021-01-26]. doi:10.1016/j.bmcl.2017.06.004. （原始内容存档于2020-02-27） （英语）.
- ^ E. A. Ivleva, M. R. Baimuratov, M. R. Demidov, A. V. Lukashenko, Yu. A. Malinovskaya, Yu. N. Klimochkin, V. A. Tyshchenko, I. A. Kulikova, V. V. Pozdnyakov, K. A. Ovchinnikov, K. B. Rudyak. Synthesis, Physicochemical Properties, and Thermo-Oxidative Stability of Diesters of 5,7-Dimethyl-1,3-Adamantanediol and 5,7-Dimethyl-1,3-bis(Hydroxymethyl)adamantane. Petroleum Chemistry. 2018-08, 58 (8): 687–693 [2021-01-26]. ISSN 0965-5441. doi:10.1134/S096554411808008X （英语）.
- ^ Hiyoshizo Kotsuki, Yasuyuki Ushio, Naka Yoshimura, Masamitsu Ochi. Efficient Reduction of Acyl Chlorides with Zn(BH 4 ) 2 / N , N , N ′, N ′-Tetramethylethylenediamine. Bulletin of the Chemical Society of Japan. 1988-07, 61 (7): 2684–2686 [2021-01-26]. ISSN 0009-2673. doi:10.1246/bcsj.61.2684 （英语）.
- ^ Ali Md. Ahad, Song Zuohe, Lei Du-Cuny, Sylvestor A. Moses, Li Li Zhou, Shuxing Zhang, Garth Powis, Emmanuelle J. Meuillet, Eugene A. Mash. Development of sulfonamide AKT PH domain inhibitors. Bioorganic & Medicinal Chemistry. 2011-03, 19 (6): 2046–2054 [2021-01-26]. doi:10.1016/j.bmc.2011.01.049. （原始内容存档于2020-02-15） （英语）.