心律失常性猝死综合征

(重定向自突发性猝死综合征

心律失常性猝死综合征[1](sudden arrhythmic death syndrome,SADS)旧名突发性猝死综合征(sudden unexpected death syndrome,SUDS)、突发性夜间猝死综合征(sudden unexpected nocturnal death syndrome),是一种突发而不能预测的心源性死亡,经尸检、组织学、毒理学研究均不能解释的综合征,多数患者有遗传性心脏病;患此病的青少年或成人在睡眠时会突然死亡[2]布鲁格达氏综合征是其中一种相对常见的类型[3]

此综合征于1977年在美国的苗族难民中首次发现[4][5]。此后新加坡的一项回顾性调查又发现,1982年至1990年间有230名健康的泰国人因不明原因突然死亡[6]。在菲律宾本土方言中该病被称为“bangungot”(意为睡眠中呻吟),每年平均10万人中有43人因此丧命,病人多为年轻男性[7]

研究发现bangungot患者并无器质性的心脏病变,但发病时有心律不齐、心室颤动的症状。现在仍无法预防此病的发生,发病后则可以通过除颤器进行治疗。菲律宾传统上会使用扭动患者拇趾的方法使其心律恢复正常[8]

菲律宾的大多bangungot病例与急性出血性胰腺炎(acute hemorrhagic pancreatitis)有关[9]泰国老挝的bangungot则由布魯格達氏症候群导致[10]

参见 编辑

参考文献 编辑

  1. ^ 帅维,洪葵. 心律失常性猝死成人和儿童家族成员的临床管理[J]. 临床心血管病杂志,2015,31(12):1259-1261. DOI:10.13201/j.issn.1001-1439.2015.12.003.
  2. ^ Also known as SUDS. See: Reddy PR, Reinier K, Singh T, Mariani R, Gunson K, Jui J, Chugh SS. Physical activity as a trigger of sudden cardiac arrest: The Oregon Sudden Unexpected Death Study. Int J Cardiol. 2008
  3. ^ Brugada Syndrome. NORD (National Organization for Rare Disorders). 2016 [28 October 2017]. (原始内容存档于2017-02-11). 
  4. ^ Centers for Disease Control (CDC). Sudden, unexpected, nocturnal deaths among Southeast Asian refugees. MMWR. Morbidity and mortality weekly report. 1981, 30 (47): 581–4,589. PMID 6796814. 
  5. ^ Parrish RG, Tucker M, Ing R, Encarnacion C, Eberhardt M. Sudden unexplained death syndrome in Southeast Asian refugees: a review of CDC surveillance. MMWR CDC Surveil Summ. 1987, 36 (1): 43SS–53SS. PMID 3110586. 
  6. ^ Goh KT, Chao TC, Chew CH. Sudden nocturnal deaths among Thai construction workers in Singapore. Lancet. 1990, 335 (8698): 1154. PMID 1971883. doi:10.1016/0140-6736(90)91153-2. 
  7. ^ Gervacio-Domingo, G.; F . Punzalan , M . Amarillo , A . Dans. Sudden unexplained death during sleep occurred commonly in the general population in the Philippines: a sub study of the National Nutrition and Health Survey .. Journal of Clinical Epidemiology: 561–571. [2008-12-09]. (原始内容存档于2018-07-01). 
  8. ^ Ramos, Maximo D. Creatures of Philippine Lower Mythology. Philippines: University of the Philippines Press. 1971. 
  9. ^ Munger, Ronald G.; Elizabeth A. Booton. Bangungut in Manila: sudden and unexplained death in sleep of adult Filipinos (PDF). International Journal of Epidemiology. 1998, 27 (4): 677–684 [2011-07-29]. PMID 9758125. doi:10.1093/ije/27.4.677. (原始内容 (PDF)存档于2015-09-30). 
  10. ^ http://www.inq7.net/lif/2004/jun/19/lif_7-1.htm (link broken as of 3 October 2007).. [2012-04-27]. (原始内容存档于2004-06-30).  外部链接存在于|title= (帮助)