吡啶-2-甲酸铬

吡啶-2-甲酸铬
Ball and Stick model of chromium (III) picolinate	Spacefill model of chromium (III) picolinate
	IUPAC名; Tris(picolinate)chromium(III)
别名	2-吡啶甲酸铬; 2-吡啶羧酸铬; 吡啶-2-羧酸铬
识别
CAS号	14639-25-9
PubChem	151932
ChemSpider	133913
SMILES	c1ccnc(c1)C(=O)[O-].c1ccnc(c1)C(=O)[O-].c1ccnc(c1)C(=O)[O-].[Cr+3];
InChI	1/3C6H5NO2.Cr/c38-6(9)5-3-1-2-4-7-5;/h31-4H,(H,8,9);/q;;;+3/p-3;
InChIKey	CBDQOLKNTOMMTL-DFZHHIFOAM
ChEBI	50369
性质
化学式	Cr(C6H4NO2)3
摩尔质量	418.33 g/mol g·mol⁻¹
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

吡啶-2-甲酸铬（简写：CrPic₃）是一种化合物，用作营养补充剂以治疗2型糖尿病，以及促进减肥。^[1] 它是红粉色的化合物，最初于1917年报道。^[2]^[3]它难溶于水，在中性pH下的水中，溶解度为600 µmol/L。^[4]它和其它三价铬化合物类似，化学性质上具有惰性，即在一般条件下稳定，它仅在较高温度下分解。^[5]在较低的pH下，该配合物会游离出吡啶-2-甲酸和Cr³⁺离子。^[4]

参考文献编辑

^ Preuss, H. G.; Echard, B.; Perricone, N. V.; Bagchi, D.; Yasmin, T.; Stohs, S. J. Comparing metabolic effects of six different commercial trivalent chromium compounds. Journal of Inorganic Biochemistry. 2008, 102 (11): 1986–1990. PMID 18774175. doi:10.1016/j.jinorgbio.2008.07.012.
^ Vincent, John (2010). "Chromium: celebrating 50 years as an essential element?". Dalton Transactions. Royal Society of Chemistry. 39: 3787–3794. doi:10.1039/B920480F. PMID 20372701. Retrieved 20 March 2015.
^ Vincent, John. The Bioinorganic Chemistry of Chromium (III). Polyhedron (Elsevier B.V). 2001, 20: 1–26 [20 March 2015]. doi:10.1016/S0277-5387(00)00624-0. （原始内容存档于2015-09-24）.
^ ^4.0 ^4.1 Feng, Weiyue (2007). "Chapter 6—The Transport of chromium (III) in the body: Implications for Function". In Vincent, John. The Nutritional Biochemistry of Chromium (III) (PDF). Amsterdam: Elsevier B.V. pp. 121–137. ISBN 978-0-444-53071-4. Retrieved 20 March 2015.
^ Abou–Gamra, Zeinab; Abdel–Messih, Michel. Correlation of thermal and spectral properties of chromium(III) picolinate complex and kinetic study of its thermal degradation. Journal of Thermal Analysis and Calorimetry (Springer Netherlands). 2014, 117 (2): 993–1000 [1 April 2015]. doi:10.1007/s10973-014-3768-5. （原始内容存档于2019-07-30）.

拓展链接编辑

[1] Preuss, H. G.; Echard, B.; Perricone, N. V.; Bagchi, D.; Yasmin, T.; Stohs, S. J. Comparing metabolic effects of six different commercial trivalent chromium compounds. Journal of Inorganic Biochemistry. 2008, 102 (11): 1986–1990. PMID 18774175. doi:10.1016/j.jinorgbio.2008.07.012.

[Cr50yr-2] Vincent, John (2010). "Chromium: celebrating 50 years as an essential element?". Dalton Transactions. Royal Society of Chemistry. 39: 3787–3794. doi:10.1039/B920480F. PMID 20372701. Retrieved 20 March 2015.

[Vincent2001-3] Vincent, John. The Bioinorganic Chemistry of Chromium (III). Polyhedron (Elsevier B.V). 2001, 20: 1–26 [20 March 2015]. doi:10.1016/S0277-5387(00)00624-0. （原始内容存档于2015-09-24）.

[Feng-4] 4.0 ^4.1 Feng, Weiyue (2007). "Chapter 6—The Transport of chromium (III) in the body: Implications for Function". In Vincent, John. The Nutritional Biochemistry of Chromium (III) (PDF). Amsterdam: Elsevier B.V. pp. 121–137. ISBN 978-0-444-53071-4. Retrieved 20 March 2015.

[Abou2014-5] Abou–Gamra, Zeinab; Abdel–Messih, Michel. Correlation of thermal and spectral properties of chromium(III) picolinate complex and kinetic study of its thermal degradation. Journal of Thermal Analysis and Calorimetry (Springer Netherlands). 2014, 117 (2): 993–1000 [1 April 2015]. doi:10.1007/s10973-014-3768-5. （原始内容存档于2019-07-30）.

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吡啶-2-甲酸铬

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