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心理藥物學(英文:Psychopharmacology )是指以科學方法研究預備、使用心理疾病藥物及這些藥物的效用。心理疾病相關藥物稱為psychotropic medications(psycho:心理的;tropic:作用於)。

主要概念[1]编辑

基本概念编辑

常見不跟從服藥指示原因[5]
  • 以為很快見效,但抗抑鬱藥要至少2星期才見效
  • 麻煩、工作上不便,或影響生計
  • 服藥等於軟弱
  • 以為會根治,但有的藥物只是爭取時間來讓病患有更多精力去處理問題
  • 享受藥物的舒緩效果,如服用巴比妥類後會很快就不緊張
  • 享受受人關注,病了有人去關心自己而繼續去病附加的好處英语Primary and secondary gain

藥物代謝動力學[7]编辑

藥物效應動力學[7]编辑

親和性 (Affinity) 效能(Efficacy)
活化劑(agonist)
阻斷劑(antagonist) 中至高

化學訊號编辑

神經遞質[21]编辑

精神作用藥物通常用神經遞質來影響神經傳導英语Neurotransmission神經遞質主要一種化學物質來讓神經元互相溝通,而精神作用藥物則影響這個溝通過程。這些藥物可以

  1. 作為神經遞質前體(precursor)(作為製造神經遞質的原材料)
  2. 壓抑神經遞質的生成
  3. 避免突触小泡英语presynaptic vesicle(presynaptic vesicle)儲存神經遞質
  4. 刺激或抑制神經遞質釋出
  5. 刺激或抑制後突觸(post-synaptic)的受體運作(Receptor)
  6. 刺激再攝取泵(autoreceptor),減少神經遞質釋出
  7. 阻礙再攝取泵(autoreceptor),增加神經遞質釋出
  8. 壓抑神經傳導英语Neurotransmission breakdown
  9. 阻礙前突觸(presynaptic)被再吸收英语reuptake(reuptake)

激素编辑

常見心理藥物编辑

相關期刊编辑

參考來源编辑

  1. ^ L., Hart, Carl. Drugs, society & human behavior 15th ed. New York, NY: McGraw-Hill. 2013. ISBN 9780073529745. OCLC 808107397. 
  2. ^ editor., Kandel, Eric R. Mack, Sarah, art. Principles of neural science. ISBN 9780071390118. OCLC 918899790. 
  3. ^ Greengard, P. The neurobiology of slow synaptic transmission. Science (New York, N.Y.). 2001-11-02, 294 (5544): 1024–1030. ISSN 0036-8075. PMID 11691979. doi:10.1126/science.294.5544.1024. 
  4. ^ CDC. Disease of the Week - Alcohol and Pregnancy. Centers for Disease Control and Prevention. 2017-09-06 [2019-03-21] (美国英语). 
  5. ^ 4. Principles of Psychopharmacology for Mental Health Professionals. Hoboken, NJ, USA: John Wiley & Sons, Inc. 2005-10-07: 9–35. ISBN 9780471794639. 
  6. ^ 保安局禁毒處 - 戒毒治療和康復服務戒毒治療和康復服務. www.nd.gov.hk. [2019-03-21]. 
  7. ^ 7.0 7.1 1947-, Meyer, Jerrold S.,; A.,, Rice, Susan; R.,, Yates, Jennifer. 2,3. Psychopharmacology : drugs, the brain, and behavior Second edition. Sunderland, Massachusetts. ISBN 087893510X. OCLC 819641635. 
  8. ^ Wesley McCammon, Fluid Mosaic Model of the Cell Membrane, 2009-07-19 [2019-03-21] 
  9. ^ Khutoryanskiy, Vitaliy V. Longer and safer gastric residence. Nature Materials. 2015-10, 14 (10): 963–964. ISSN 1476-1122. doi:10.1038/nmat4432. 
  10. ^ Carbon Oxidation. learn.genetics.utah.edu. [2019-03-21]. 
  11. ^ Nucleus Medical Media, Biology: Cell Structure I Nucleus Medical Media, 2015-03-18 [2019-03-21] 
  12. ^ What Is A Standard Drink? | National Institute on Alcohol Abuse and Alcoholism (NIAAA). www.niaaa.nih.gov. [2019-03-19]. 
  13. ^ Sinauer Associates, Inc., Publishers. www.sinauer.com. [2019-03-19]. 
  14. ^ Purple Haze of Parkinson’s: How Dopamine Works. Journey with Parkinson's. 2015-08-05 [2019-03-19] (英语). 
  15. ^ 2. General Mechanisms of the Endocrine Regulation • Functions of Cells and Human Body. [2019-03-21] (美国英语). 
  16. ^ About Huntington's Disease and Serotonin. HOPES Huntington's Disease Information. 2011-06-30 [2019-03-21] (美国英语). 
  17. ^ Pharmapedia, Agonist Dose Response Curves, 2015-06-11 [2019-03-21] 
  18. ^ basic_principles_of_pharm [TUSOM | Pharmwiki]. tmedweb.tulane.edu. [2019-03-21] (英语). 
  19. ^ ToxTutor - Determining the Safety of a Drug. toxtutor.nlm.nih.gov. [2019-03-21]. 
  20. ^ Pharmapedia, Efficacy vs Potency, 2015-06-15 [2019-03-19] 
  21. ^ W,, Kalat, James. Biological psychology 12 e. Australia. : 49–57. ISBN 9781305105409. OCLC 898154491.