3-甲氧基安非他命

化合物

間甲氧基安非他命[1]MMA ),也称为3-甲氧基安非他命3-MA ),是一种安非他命類的興奮劑。它在动物药物鉴别测试中的作用与更廣为人知的位置異構物4-甲氧基安非他命(PMA)相似 [2],儘管其導致的單胺類神經遞質释放比率略有不同,且它是血清素多巴胺去甲基腎上腺素释放剂,而不是如PMA的結合选择性血清素释放剂[3] [4] 3-甲氧基安非他命以类似的方式作为摇头丸設計毒品出现在非法市场上,尽管比其臭名昭著的位置异构体少得多。 [5]它的代謝產物Gepefrine ,一种心脏兴奋剂。 [6]

3-甲氧基安非他命
3-Methoxyamphetamine.png
系统(IUPAC)命名名称
1-(3-甲氧基苯基)丙-2-胺
临床数据
给药途径口服
识别信息
CAS注册号17862-85-0  ☒N
ATC代码
PubChemCID 152234
ChemSpider134180 ✓
ChEMBL英语ChEMBLCHEMBL16247 ✓
化学信息
化学式C10H15NO
摩尔质量165.24 g·mol−1

相關條目编辑

参考資料编辑

  1. ^ 1527479 
  2. ^ Structure-activity studies on methoxy-substituted phenylisopropylamines using drug discrimination methodology. Pharmacology, Biochemistry, and Behavior. May 1985, 22 (5): 723–9. PMID 3839309. doi:10.1016/0091-3057(85)90520-9. 
  3. ^ Comparative actions of monomethoxyamphetamines on the release and uptake of biogenic amines in brain tissue. The Journal of Pharmacology and Experimental Therapeutics. May 1976, 197 (2): 263–71. PMID 1271280. 
  4. ^ Pharmacological evidence for the central serotonergic effects of monomethoxyamphetamines. The Journal of Pharmacology and Experimental Therapeutics. May 1976, 197 (2): 272–9. PMID 946817. 
  5. ^ A re-examination of the mono-methoxy positional ring isomers of amphetamine, methamphetamine and phenyl-2-propanone. Forensic Science International. June 2001, 119 (2): 168–94. PMID 11376983. doi:10.1016/S0379-0738(00)00425-4. 
  6. ^ The metabolism of 3-methoxyamphetamine in dog, monkey and man. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. February 1981, 11 (2): 137–46. PMID 6894510. doi:10.3109/00498258109045284.