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English: Coronaviruses structures. The membrane (M), envelope (E) and spike (S) structural proteins are anchored to the viral envelope which contains the ribonucleoprotein core, i.e., the nucleocapsid protein (N) which acts as a scaffold surrounding the single-stranded RNA. b The surface spike is composed by the S1 subunit, which harbors the receptor binding domain (RBD), and by the S2 subunit, the stem which anchors the spike to the viral envelope and, following protease activation, enables host cell fusion.
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来源 Rossi, G.A., Sacco, O., Mancino, E. et al. Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. Infection 48, 665–669 (2020). https://doi.org/10.1007/s15010-020-01486-5
作者 Giovanni A. Rossi, Oliviero Sacco, Enrica Mancino, Luca Cristiani, and Fabio Midulla

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Coronaviruses structures.

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