SOX基因家族(英語:SOX gene family,即SRY相关HMG盒基因家族SRY-related HMG-box genes)是一类高速泳动族转录因子[1]

SOXB subfamily, C-terminal next to HMG box
鑑定
標誌SOXp
PfamPF12336旧版
InterPro英语InterProIPR022097
SOXE, N-terminal
鑑定
標誌Sox_N
PfamPF12444旧版
InterPro英语InterProIPR022151
SOXF, C-terminal, 9aaTAD
鑑定
標誌SOX_C
InterPro英语InterProIPR021934
PROSITE英语PROSITEPS51516
SOXF, central
鑑定
標誌Sox17_18_mid
PfamPF12067旧版
InterPro英语InterProIPR033392

人类基因组拥有SRY等20个SOX家族成员,如下[2]

参考文献 编辑

  1. ^ Bowles, J; Schepers G; Koopman P. Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators.. Dev. Biol. November 2000, 227 (2): 239–55. PMID 11071752. doi:10.1006/dbio.2000.9883 . 
  2. ^ Guth SI, Wegner M. Having it both ways: Sox protein function between conservation and innovation. Cell. Mol. Life Sci. October 2008, 65 (19): 3000–18. PMID 18516494. S2CID 8943181. doi:10.1007/s00018-008-8138-7. 

外部链接 编辑