葛根素

化合物

葛根素Puerarin)是一種異黃酮,存在於多種植物,包括一些藥用植物中,尤其是葛屬植物的根莖,例如中藥葛根,以及三裂葉葛藤[1]

葛根素
IUPAC名
7-Hydroxy-3-(4-hydroxyphenyl)-8-[(3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
別名 Daidzein-8-C-glucoside
7,4'-Dihydroxy-8-C-glucosylisoflavone
識別
CAS號 3681-99-0  checkY
PubChem 5486172
ChemSpider 4445119
SMILES
 
  • C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O
性質
化學式 C21H20O9
摩爾質量 416.38 g·mol−1
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

葛根素是大豆苷元的8-C-葡萄糖苷[2]

參考資料

編輯
  1. ^ Dennis K.Y. Yeunga; Susan W.S. Leung; Yan Chun Xua; Paul M. Vanhouttea; Ricky Y.K. Mana. Puerarin, an isoflavonoid derived from Radix puerariae, potentiates endothelium-independent relaxation via the cyclic AMP pathway in porcine coronary artery. European Journal of Pharmacology. 2006, 552 (1–3): 105–11. PMID 17027964. doi:10.1016/j.ejphar.2006.08.078. 
  2. ^ Overstreet DH, Kralic JE, Morrow AL, Ma ZZ, Zhang YW, Lee DY. NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacology, biochemistry, and behavior英語Pharmacology, biochemistry, and behavior. 2003, 75 (3): 619–625. PMID 12895679. doi:10.1016/S0091-3057(03)00114-X.