5-正十五烷基间苯二酚

化合物

5-正十五烷基间苯二酚(英语:5-Pentadecylresorcinol,也称作Adipostatin A)是一种天然烷基间苯二酚类化合物[3],最早提取自放线菌Streptomyces cyaneus[4],后在银杏的果实、兰屿树杞中都有发现[5]

5-正十五烷基间苯二酚
Chemical structure of adipostatin A
IUPAC名
5-Pentadecylbenzene-1,3-diol
别名 Cardol
5-n-Pentadecylresorcinol
5-Pentadecylresorcinol
识别
CAS号 3158-56-3  checkY
PubChem 76617
ChemSpider 69081
SMILES
 
  • CCCCCCCCCCCCCCCC1=CC(=CC(=C1)O)O
InChI
 
  • 1/C21H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-16-20(22)18-21(23)17-19/h16-18,22-23H,2-15H2,1H3
InChIKey KVVSCMOUFCNCGX-UHFFFAOYAU
性质
化学式 C21H36O2
摩尔质量 320.51 g·mol−1
熔点 91 °C(364 K)[1]
溶解性 3.8×10−5 g(25 °C)[2]
pKa 9.55±0.10(25 °C)[2]
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

编辑
  1. ^ Kirsti Parikka, Kristiina Wähälä. An expedient synthesis of 5- n -alkylresorcinols and novel 5- n -alkylresorcinol haptens. Beilstein Journal of Organic Chemistry. 2009-05-19, 5 [2021-01-13]. ISSN 1860-5397. PMC 2707013 . PMID 19590737. doi:10.3762/bjoc.5.22. (原始内容存档于2018-06-02) (英语). 
  2. ^ 2.0 2.1 Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 ((C) 1994-2021 ACD/Labs). Retrieved from SciFinder. [2021-01-13]
  3. ^ 杨丽娟; 武利强; 杨春广. Adipostatin A的简易合成. 河南职工医学院学报. 2008, (5): 429–431. ISSN 1008-9276. CNKI HNZG200805005. 
  4. ^ Tanaka, A; Arai, Y; Kim, SN; Ham, J; Usuki, T. Synthesis and biological evaluation of bilobol and adipostatin A. Journal of Asian Natural Products Research. 2011, 13 (4): 290–6. PMID 21462031. S2CID 25305504. doi:10.1080/10286020.2011.554828. 
  5. ^ Koh Hwee Ling, Chua Tung Kian, and Tan Chay Hoon. "A Guide to Medicinal Plants: An Illustrated, Scientific and Medicinal Approach", p. 14. World Scientific Publishing 2009, ISBN 981-283-709-4. Preview available at Google Books