杀鼠酮

化合物

杀鼠酮(英语:Pindone)是一种1,3-茚满二酮维生素K拮抗剂英语Vitamin K antagonist抗凝剂[3],分子式为C14H14O3,在农业上用作灭鼠剂

杀鼠酮
IUPAC名
2-(2,2-Dimethylpropanoyl)-1H-indene-1,3(2H)-dione
别名 2-Pivaloyl-1,3-indandione
识别
CAS号 83-26-1  checkY
PubChem 6732
ChemSpider 6476
SMILES
 
  • O=C2c1ccccc1C(=O)C2C(=O)C(C)(C)C
InChI
 
  • 1/C14H14O3/c1-14(2,3)13(17)10-11(15)8-6-4-5-7-9(8)12(10)16/h4-7,10H,1-3H3
InChIKey RZKYEQDPDZUERB-UHFFFAOYAX
KEGG C19141
性质
化学式 C14H14O3
摩尔质量 230.26 g/mol g·mol⁻¹
外观 Bright-yellow powder[1]
气味 almost none
密度 1.06 g/mL
熔点 110 °C(383 K)
溶解性 0.002% (25°C)[1]
危险性
PEL TWA 0.1 mg/m3[1]
致死量或浓度:
LD50中位剂量
280 mg/kg (rat, oral)
75 mg/kg (dog, oral)
150 mg/kg (rabbit, oral)[2]
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

编辑
  1. ^ 1.0 1.1 1.2 NIOSH Pocket Guide to Chemical Hazards. #0516. NIOSH. 
  2. ^ Pindone. Immediately Dangerous to Life and Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH). 
  3. ^ Robinson MH, Twigg LE, Wheeler SH, Martin GR. Effect of the anticoagulant, pindone, on the breeding performance and survival of merino sheep, Ovis aries. Comp. Biochem. Physiol. B. March 2005, 140 (3): 465–73. PMID 15694595. doi:10.1016/j.cbpc.2004.11.011.