老化防護
老化防護指的是一類以老化和老化相關疾病的肇因為目標、因而可能延長動物壽命的老化防護療法。[1][2][3]一些可能的老化防護藥物包括了褪黑激素[4]、肌肽[5]、二甲双胍[6]、煙醯胺單核苷酸（nicotinamide mononucleotide，縮寫為NMN）[7][8]和δ睡眠肽 （delta sleep-inducing peptide）[9]等等。
參照 编辑
- ^ De-novo geroprotector design （页面存档备份，存于互联网档案馆）, SENS Foundation
- ^ Alexey Moskalev, Elizaveta Chernyagina, Anna Kudryavtseva & Mikhail Shaposhnikov. Geroprotectors: A Unified Concept and Screening Approaches. Aging and Disease. 2017, 8 (3): 354–363. PMC 5440114
. PMID 28580190. doi:10.14336/AD.2016.1022.
- ^ Alexey Moskalev, Elizaveta Chernyagina, Joao Pedro de Magalhaes & Alex Zhavoronkov. Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease. Aging. 2015, 7 (9): 616–628. PMC 4600621 . PMID 26342919. doi:10.18632/aging.100799.
- ^ Anisimov, VN; Popovich, IG; Zabezhinski, MA; Anisimov, SV; Vesnushkin, GM; Vinogradova, IA. Melatonin as antioxidant, geroprotector and anticarcinogen. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 2006, 1757 (5–6): 573–89. PMID 16678784. doi:10.1016/j.bbabio.2006.03.012.
- ^ Boldyrev, AA; Stvolinsky, SL; Fedorova, TN; Suslina, ZA. Carnosine as a natural antioxidant and geroprotector: From molecular mechanisms to clinical trials. Rejuvenation Research. 2010, 13 (2–3): 156–8. PMID 20017611. doi:10.1089/rej.2009.0923.
- ^ Bulterijs, S. Metformin As a Geroprotector. Rejuvenation Research. 2011, 14 (5): 469–82. PMID 21882902. S2CID 40645408. doi:10.1089/rej.2011.1153.
- ^ Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice, Cell Metabolism 24, 795–806, December 13, 2016 ª 2016 Elsevier Inc.
- ^ 長壽藥”NMN腫瘤能不能喫？不得不說的NMN副作用大全. 互動頭條. [2020-11-30]. （原始内容存档于2020-12-11） （中文（臺灣））.
- ^ Bondarenko, TI. Mechanism of delta-sleep inducing peptide geroprotective activity. Adv Gerontol. 2011, 24 (1): 80–92. PMID 21809625.
參見 编辑
外部連結 编辑
- Geroprotectors （页面存档备份，存于互联网档案馆）─一個關於老化防護藥物資料庫。
- Aging Chart （页面存档备份，存于互联网档案馆）─一個由社群管理的和老化相關的生化路徑與知識的集合。
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