4-羟基苯甲醛

化合物

4-羟基苯甲醛是一种有机化合物,化学式为C7H6O2,存在于天麻[1]、山珊瑚[2]香荚兰中。它可由4-羟基苯甲醇的催化氧化反应制得。[3][4]它和乙酸酐反应,可以得到4-乙酰氧基苯甲醛[5]

4-羟基苯甲醛
别名 对羟基苯甲醛
识别
CAS号 123-08-0  ✓
PubChem 126
ChemSpider 123
SMILES
InChI
InChIKey RGHHSNMVTDWUBI-UHFFFAOYAN
ChEBI 17597
DrugBank DB03560
KEGG C00633
性质
化学式 C7H6O2
摩尔质量 122.12 g·mol−1
外观 浅黄色粉末
密度 1.226 ± 0.06 g/cm3
熔点 112-116 °C(385-389 K)
沸点 310-311 °C(583-584 K)
磁化率 -78.0·10−6 cm3/mol
若非注明,所有数据均出自一般条件(25 ℃,100 kPa)下。

参考文献编辑

  1. ^ Ha, J. H.; Lee, D. U.; Lee, J. T.; Kim, J. S.; Yong, C. S.; Kim, J. A.; Ha, J. S.; Huh, K. 4-Hydroxybenzaldehyde from Gastrodia elata B1. Is active in the antioxidation and GABAergic neuromodulation of the rat brain. Journal of Ethnopharmacology. 2000, 73 (1–2): 329–333. PMID 11025174. doi:10.1016/S0378-8741(00)00313-5. 
  2. ^ Li, Y. M.; Zhou, Z. L.; Hong, Y. F. (title in Chinese) [Studies on the phenolic derivatives from Galeola faberi Rolfe]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 1993, 28 (10): 766–771. PMID 8009989 (中文). 
  3. ^ SyedF. Adil, MohamedE. Assal, Mufsir Kuniyil, Mujeeb Khan, Mohammed Rafi Shaik, Abdulrahman Alwarthan, JoselitoP. Labis, Mohammed RafiqH. Siddiqui. Synthesis and comparative catalytic study of zinc oxide (ZnO x ) nanoparticles promoted MnCO 3 , MnO 2 and Mn 2 O 3 for selective oxidation of benzylic alcohols using molecular oxygen. Materials Express. 2017-04-01, 7 (2): 79–92 [2021-05-21]. ISSN 2158-5849. doi:10.1166/mex.2017.1357 (英语). 
  4. ^ Eduardo Buxaderas, Marilyn Graziano-Mayer, María Volpe, Gabriel Radivoy. Bimetallic Cu-Pd Nanoparticles Supported on Bio-silica as an Efficient Catalyst for Selective Aerobic Oxidation of Benzylic Alcohols. Synthesis. 2016-10-21, 49 (06): 1387–1393 [2021-05-21]. ISSN 0039-7881. doi:10.1055/s-0036-1588628. (原始内容存档于2018-06-02) (英语). 
  5. ^ Karol Kraszewski, Ireneusz Tomczyk, Aneta Drabinska, Krzysztof Bienkowski, Renata Solarska, Marcin Kalek. Mechanism of Iodine(III)‐Promoted Oxidative Dearomatizing Hydroxylation of Phenols: Evidence for a Radical‐Chain Pathway. Chemistry – A European Journal. 2020-09-04, 26 (50): 11584–11592 [2021-05-21]. ISSN 0947-6539. doi:10.1002/chem.202002026 (英语).