5-氯吲哚-3-甲醛

化合物

5-氯吲哚-3-甲醛是一种有机化合物,化学式为C9H6ClNO。它可由5-氯吲哚二甲基甲酰胺三氯氧磷的存在下反应得到。[2]它和硝基甲烷反应,可以得到5-氯-3-(2-硝基乙烯基)吲哚。[3]它和苯磺酰氯反应,可以得到5-氯-1-苯磺酰基吲哚-3-甲醛。[4]

5-氯吲哚-3-甲醛
识别
CAS号 827-01-0  checkY
性质
化学式 C9H6ClNO
摩尔质量 179.6 g·mol−1
熔点 215—216 °C(488—489 K)[1]
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

编辑
  1. ^ Edwin H. P. Young. 704. The synthesis of 5-hydroxytryptamine (serotonin) and related tryptamines. Journal of the Chemical Society (Resumed). 1958: 3493 [2021-10-20]. ISSN 0368-1769. doi:10.1039/jr9580003493 (英语). 
  2. ^ Kai Liu, Yangyang Ding, Congmin Kang. Synthesis and Antiproliferative Activity of New N-Acylhydrazone Derivatives Containing Benzothiazole and Indole Based Moiety. Pharmaceutical Chemistry Journal. 2020-07, 54 (4): 345–352 [2021-10-20]. ISSN 0091-150X. doi:10.1007/s11094-020-02215-w (英语). 
  3. ^ Sape S. Kinderman, Monique M. T. Wekking, Jan H. van Maarseveen, Hans E. Schoemaker, Henk Hiemstra, Floris P. J. T. Rutjes. Catalytic N -Sulfonyliminium Ion-Mediated Cyclizations to α-Vinyl-Substituted Isoquinolines and β-Carbolines and Applications in Metathesis. The Journal of Organic Chemistry. 2005-07-01, 70 (14): 5519–5527 [2021-10-20]. ISSN 0022-3263. doi:10.1021/jo050503t. (原始内容存档于2021-10-20) (英语). 
  4. ^ Ming-Zhi Zhang, Qiong Chen, Cai-Hong Xie, Nick Mulholland, Sarah Turner, Dianne Irwin, Yu-Cheng Gu, Guang-Fu Yang, John Clough. Synthesis and antifungal activity of novel streptochlorin analogues. European Journal of Medicinal Chemistry. 2015-03, 92: 776–783 [2021-10-20]. doi:10.1016/j.ejmech.2015.01.043. (原始内容存档于2018-06-12) (英语).