PX结构域(英語:PX domain)是一类蛋白质结构域,能通过结合磷脂酰肌醇Phosphatidylinositol,PI)使蛋白定位到细胞膜上,最早在NADH氧化酶p40phox中发现[1][2]

NADH氧化酶p40phox的PX结构域
鑑定
標誌PX
PfamPF00787旧版
InterPro英语InterProIPR001683
SMART英语Simple Modular Architecture Research ToolPX
PROSITE英语PROSITEPDOC50195
SCOP英语Structural Classification of Proteins1h6h / SUPFAM
OPM英语Orientations of Proteins in Membranes database家族57
OPM英语Orientations of Proteins in Membranes database蛋白1xte
CDD英语Conserved Domain Databasecd06093

参考文献

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  1. ^ Ponting CP. Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3-kinases: binding partners of SH3 domains?. Protein Sci. November 1996, 5 (11): 2353–7. PMC 2143296 . PMID 8931154. doi:10.1002/pro.5560051122. 
  2. ^ Wishart MJ, Taylor GS, Dixon JE. Phoxy lipids: revealing PX domains as phosphoinositide binding modules. Cell. June 2001, 105 (7): 817–20. PMID 11439176. S2CID 12622490. doi:10.1016/S0092-8674(01)00414-7. 

外部链接

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