This is an image of murine CTLA4 (CD152) which is necessary for inhibiting the T cells. It binds to CD28 with a higher affinity than the costimulatory molecules CD80 and CD86. This image is derived from Protein Data Bank data 1DQT which was published by Ostrov et al. in 2000. I rendered the image in PyMol myself based on the published pdb file.

For the published pdb, please see: Ostrov, D.A., Shi, W., Schwartz, J.C., Almo, S.C., Nathenson, S.G. Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science v290 pp.816-819 , 2000.

描述CTLA4 Crystal Structure.rsh.png	Crystal structure of CTLA4 as published in the Protein Data Bank (PDB: 1DQT)
日期	2006年10月12日
來源	Created from PDB 1DQT and rendered by me using Pymol
作者	Ramin Herati
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