合胞素-2

合胞素-2
已知的結構
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	1Y4M
識別號
别名	ERVFRD-1；, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD, UNQ6191, envFRD, endogenous retrovirus group FRD member 1, endogenous retrovirus group FRD member 1, envelope
外部ID	OMIM：610524 MGI：3045308 HomoloGene：86779 GeneCards：ERVFRD-1
基因位置（人类）
染色体	6號染色體
终止	11,111,725 bp
基因位置（小鼠）
染色体	小鼠14号染色体
终止	69,531,748 bp
直系同源
	405754
	239167
	ENSG00000244476
	ENSMUSG00000047977
	P60508
	Q8BI41
	NM_207582
	NM_173420
	NP_997465
	NP_775596
	維基數據
檢視/編輯人類	檢視/編輯小鼠

合胞素-2（英語：Syncytin-2，也称为內源性反轉錄病毒FRD组成员1，endogenous retrovirus group FRD member 1），它由ERVFRD-1基因编码^[5]，与胚胎在子宫中的着床有关^[6]。該基因是一种内源性病毒元件，它是约4500万年前逆转录病毒感染人類後的残余物^[7]。

参考文献编辑

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000244476 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000047977 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Entrez Gene: HERV-FRD HERV-FRD provirus ancestral Env polyprotein.
^ Vargas A, Moreau J, Landry S, LeBellego F, Toufaily C, Rassart E, Lafond J, Barbeau B. Syncytin-2 plays an important role in the fusion of human trophoblast cells. Journal of Molecular Biology. 2009, 392 (2): 301–18. PMID 19616006. doi:10.1016/j.jmb.2009.07.025.
^ Lavialle C, Cornelis G, Dupressoir A, Esnault C, Heidmann O, Vernochet C, Heidmann T. Paleovirology of 'syncytins', retroviral env genes exapted for a role in placentation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. September 2013, 368 (1626): 20120507. PMC 3758191  . PMID 23938756. doi:10.1098/rstb.2012.0507.

外部鏈接编辑

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000244476 - Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000047977 - Ensembl, May 2017

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] Entrez Gene: HERV-FRD HERV-FRD provirus ancestral Env polyprotein.

[pmid19616006-6] Vargas A, Moreau J, Landry S, LeBellego F, Toufaily C, Rassart E, Lafond J, Barbeau B. Syncytin-2 plays an important role in the fusion of human trophoblast cells. Journal of Molecular Biology. 2009, 392 (2): 301–18. PMID 19616006. doi:10.1016/j.jmb.2009.07.025.

[pmid23938756-7] Lavialle C, Cornelis G, Dupressoir A, Esnault C, Heidmann O, Vernochet C, Heidmann T. Paleovirology of 'syncytins', retroviral env genes exapted for a role in placentation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. September 2013, 368 (1626): 20120507. PMC 3758191  . PMID 23938756. doi:10.1098/rstb.2012.0507.

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合胞素-2

参考文献 编辑

外部鏈接 编辑

参考文献编辑

外部鏈接编辑