3α(17β)-羟基类固醇脱氢酶 (NAD+)
3α(17β)-羟基类固醇脱氢酶 (NAD+)（英語：3α(17β)-Hydroxysteroid dehydrogenase (NAD+)，EC 1.1.1.239），原称作睾酮17β-脱氢酶（EC 1.1.1.63），是一种以NAD+或NADP+为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下酶促反应：
| 3α(17β)-羟基类固醇脱氢酶 (NAD+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| 识别码 | |||||||||
| EC編號 | 1.1.1.63 | ||||||||
| CAS号 | 9028-62-0 | ||||||||
| 数据库 | |||||||||
| IntEnz | IntEnz浏览 | ||||||||
| BRENDA | BRENDA入口 | ||||||||
| ExPASy | NiceZyme浏览 | ||||||||
| KEGG | KEGG入口 | ||||||||
| MetaCyc | 代谢路径 | ||||||||
| PRIAM | 概述 | ||||||||
| PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
| 基因本体 | AmiGO / EGO | ||||||||
| |||||||||
参考文献
编辑- ENDAHL GL, KOCHAKIAN CD, HAMM D. Separation of a triphosphopyridine nucleotide-specific from a diphosphopyridine nucleotide-specific 17 beta-hydroxy-(testosterone) dehydrogenase of guinea pig liver. J. Biol. Chem. 1960, 235: 2792–6. PMID 13696735.
- SWEAT ML, SAMUELS LT, LUMRY R. Preparation and characterization of the enzyme which converts testosterone to androstenedione. J. Biol. Chem. 1950, 185 (1): 75–84. PMID 15436478.
- Villee CA and Spencer JM. Some properties of the pyridine nucleotide-specific 17beta-hydroxy steroid dehydrogenase of guinea pig liver. J. Biol. Chem. 1960, 235: 3615–3619. PMID 13781425.