4-溴溴苄
4-溴溴苄是一种有机化合物，化学式为C7H6Br2。它可由4-溴甲苯和N-溴代丁二酰亚胺在偶氮二异丁腈或过氧化苯甲酰存在下于四氯化碳或碳酸二乙酯中反应制得；[3][4]4-溴苯甲醇和三溴化磷反应也能得到4-溴溴苄。[5]它在铜修饰二氧化钛光催化剂的催化下可以发生C-C偶联反应，生成1,2-二(4-溴苯基)乙烷。[6]它和叠氮化钠反应，得到4-叠氮甲基溴苯。[7]它和硫代硫酸钠反应，得到4-溴苄基硫代硫酸钠。[8]
| 4-溴溴苄 | |
|---|---|
| |
| 别名 | 对溴溴苄 4-溴甲基溴苯 α,p-二溴甲苯 |
| 识别 | |
| CAS号 | 589-15-1 
|
| 性质 | |
| 化学式 | C7H6Br2 |
| 摩尔质量 | 249.93 g·mol−1 |
| 熔点 | 63 °C（336 K）[1] |
| 沸点 | 115—124 °C（388—397 K）（12 mmHg）[2] |
| 相关物质 | |
| 相关化学品 | 1,4-二溴苯 1,4-二(溴甲基)苯 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
参考文献 编辑
- ^ "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFinder. [2021-07-06].
- ^ Goerner, Gordon L.; Nametz, Richard C. A Study of the Peroxide-Catalyzed Chlorination of the Bromotoluenes with Sulfuryl Chloride. Journal of the American Chemical Society. 2002, 73 (6): 2940–2941. ISSN 0002-7863. doi:10.1021/ja01150a509.
- ^ Yan Zhong, Yi Xu, Ai-Xia Zhang, Xiao-Feng Li, Zhao-Ying Xu, Ping Li, Bin Wu. Synthesis and biological evaluation of aryloxyacetamide derivatives as neuroprotective agents. Bioorganic & Medicinal Chemistry Letters. 2016-05, 26 (10): 2526–2530 [2021-07-06]. doi:10.1016/j.bmcl.2016.03.094. （原始内容存档于2018-06-29） （英语）.
- ^ Subramanya R. K. Pingali, Sunil K. Upadhyay, Branko S Jursic. Microwave-assisted benzyl mono- and dibromination in diethyl carbonate as environmentally friendly alternative to radical bromination in carbon tetrachloride. Green Chemistry. 2011, 13 (4): 928 [2021-07-06]. ISSN 1463-9262. doi:10.1039/c0gc00794c （英语）.
- ^ Rajendiran Balasaravanan, Kumaraguru Duraimurugan, Jayaraman Sivamani, Viruthachalam Thiagarajan, Ayyanar Siva. Synthesis and photophysical properties of triphenylamine-based multiply conjugated star-like molecules. New Journal of Chemistry. 2015, 39 (9): 7472–7480 [2021-07-06]. ISSN 1144-0546. doi:10.1039/C5NJ00605H （英语）.
- ^ Li, Yaru; Ren, Pengju; Zhang, Dongsheng; Qiao, Wei; Wang, Dan; Yang, Xiaoqin; Wen, Xiaodong; Rummeli, Mark H.; Niemantsverdriet, Hans; Lewis, James P.; Besenbacher, Flemming; Xiang, Hongwei; Li, Yongwang; Su, Ren. Rationally Designed Metal Cocatalyst for Selective Photosynthesis of Bibenzyls via Dehalogenative C–C Homocoupling. ACS Catalysis. 2021, 11 (7): 4338–4348. ISSN 2155-5435. doi:10.1021/acscatal.1c00102.
- ^ Cutler, Alan; Ralph, Greg L.; Zuma, Nonkululeko H.; Aucamp, Janine; N’Da, David D. Synthesis and in vitro Leishmania promastigote growth inhibition efficacy of novel 4(3H)-quinazolinone derivatives. Arkivoc. 2020, 2020 (5): 39–58. ISSN 1551-7012. doi:10.24820/ark.5550190.p011.312.
- ^ Muhannad A. E. Al-Saedy, Joseph P. A. Harrity. A Practical and Versatile Method for the C–H Sulfenylation of Imidazo[1,2-a]pyridines. Synlett. 2020-07, 31 (12): 1182–1184 [2021-07-06]. ISSN 0936-5214. doi:10.1055/s-0040-1707108 （英语）.