4-溴溴苄
4-溴溴苄是一種有機化合物，化學式為C7H6Br2。它可由4-溴甲苯和N-溴代丁二酰亞胺在偶氮二異丁腈或過氧化苯甲酰存在下於四氯化碳或碳酸二乙酯中反應製得；[3][4]4-溴苯甲醇和三溴化磷反應也能得到4-溴溴苄。[5]它在銅修飾二氧化鈦光催化劑的催化下可以發生C-C偶聯反應，生成1,2-二(4-溴苯基)乙烷。[6]它和疊氮化鈉反應，得到4-疊氮甲基溴苯。[7]它和硫代硫酸鈉反應，得到4-溴苄基硫代硫酸鈉。[8]
| 4-溴溴苄 | |
|---|---|
| |
| 別名 | 對溴溴苄 4-溴甲基溴苯 α,p-二溴甲苯 |
| 識別 | |
| CAS號 | 589-15-1 
|
| 性質 | |
| 化學式 | C7H6Br2 |
| 摩爾質量 | 249.93 g·mol−1 |
| 熔點 | 63 °C（336 K）[1] |
| 沸點 | 115—124 °C（388—397 K）（12 mmHg）[2] |
| 相關物質 | |
| 相關化學品 | 1,4-二溴苯 1,4-二(溴甲基)苯 |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
參考文獻
編輯- ^ "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFinder. [2021-07-06].
- ^ Goerner, Gordon L.; Nametz, Richard C. A Study of the Peroxide-Catalyzed Chlorination of the Bromotoluenes with Sulfuryl Chloride. Journal of the American Chemical Society. 2002, 73 (6): 2940–2941. ISSN 0002-7863. doi:10.1021/ja01150a509.
- ^ Yan Zhong, Yi Xu, Ai-Xia Zhang, Xiao-Feng Li, Zhao-Ying Xu, Ping Li, Bin Wu. Synthesis and biological evaluation of aryloxyacetamide derivatives as neuroprotective agents. Bioorganic & Medicinal Chemistry Letters. 2016-05, 26 (10): 2526–2530 [2021-07-06]. doi:10.1016/j.bmcl.2016.03.094. （原始內容存檔於2018-06-29） （英語）.
- ^ Subramanya R. K. Pingali, Sunil K. Upadhyay, Branko S Jursic. Microwave-assisted benzyl mono- and dibromination in diethyl carbonate as environmentally friendly alternative to radical bromination in carbon tetrachloride. Green Chemistry. 2011, 13 (4): 928 [2021-07-06]. ISSN 1463-9262. doi:10.1039/c0gc00794c （英語）.
- ^ Rajendiran Balasaravanan, Kumaraguru Duraimurugan, Jayaraman Sivamani, Viruthachalam Thiagarajan, Ayyanar Siva. Synthesis and photophysical properties of triphenylamine-based multiply conjugated star-like molecules. New Journal of Chemistry. 2015, 39 (9): 7472–7480 [2021-07-06]. ISSN 1144-0546. doi:10.1039/C5NJ00605H （英語）.
- ^ Li, Yaru; Ren, Pengju; Zhang, Dongsheng; Qiao, Wei; Wang, Dan; Yang, Xiaoqin; Wen, Xiaodong; Rummeli, Mark H.; Niemantsverdriet, Hans; Lewis, James P.; Besenbacher, Flemming; Xiang, Hongwei; Li, Yongwang; Su, Ren. Rationally Designed Metal Cocatalyst for Selective Photosynthesis of Bibenzyls via Dehalogenative C–C Homocoupling. ACS Catalysis. 2021, 11 (7): 4338–4348. ISSN 2155-5435. doi:10.1021/acscatal.1c00102.
- ^ Cutler, Alan; Ralph, Greg L.; Zuma, Nonkululeko H.; Aucamp, Janine; N』Da, David D. Synthesis and in vitro Leishmania promastigote growth inhibition efficacy of novel 4(3H)-quinazolinone derivatives. Arkivoc. 2020, 2020 (5): 39–58. ISSN 1551-7012. doi:10.24820/ark.5550190.p011.312.
- ^ Muhannad A. E. Al-Saedy, Joseph P. A. Harrity. A Practical and Versatile Method for the C–H Sulfenylation of Imidazo[1,2-a]pyridines. Synlett. 2020-07, 31 (12): 1182–1184 [2021-07-06]. ISSN 0936-5214. doi:10.1055/s-0040-1707108 （英語）.