CYP2B6

Cytochrome P450, family 2, subfamily B, polypeptide 6
Cytochrome P450, family 2, subfamily B, polypeptide 6
有效结构
PDB	直系同源检索：PDBe, RCSB
PDB查询代码列表
	3IBD, 3QOA, 3QU8, 3UA5, 4I91, 4RQL, 4RRT
标识
代号	CYP2B6; CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450
扩展标识	遗传学：123930 鼠基因：88598 同源基因：73894 IUPHAR: ChEMBL: 4729 GeneCards: CYP2B6 Gene
EC編號	1.14.14.1
基因本体论描述
分子功能	· monooxygenase activity; · iron ion binding; · arachidonic acid epoxygenase activity; · steroid hydroxylase activity; · oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; · oxygen binding; · heme binding;
细胞成分	· cytoplasm; · endoplasmic reticulum membrane; · intracellular membrane-bounded organelle;
生物过程	· xenobiotic metabolic process; · steroid metabolic process; · drug metabolic process; · epoxygenase P450 pathway; · cellular ketone metabolic process; · exogenous drug catabolic process; · small molecule metabolic process; · oxidation-reduction process;
	Sources: Amigo / QuickGO
直系同源体
物种	人类
Entrez	1555
Ensembl	ENSG00000197408
UniProt	P20813
mRNA序列	NM_000767
蛋白序列	NP_000758
基因位置	Chr 19:; 40.99 – 41.02 Mb
PubMed查询	[1]
	查; 论; 编;

细胞色素P450 2B6（英語：Cytochrome P450 2B6）是一种由人类CYP2B6基因编码的酶。^[1] CYP2B6是细胞色素P450酶家族的一员。与CYP2A6一样，CYP2B6参与尼古丁等许多物质的代谢。^[1]

引用