异油酸是一种可以从乳制品(例如酸奶奶酪)中获得的天然ω−7反式脂肪酸

异油酸
IUPAC名
(E)-Octadec-11-enoic acid
识别
CAS号 693-72-1  checkY
PubChem 5281127
ChemSpider 4444571
SMILES
 
  • CCCCCC/C=C/CCCCCCCCCC(O)=O
InChI
 
  • 1/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h7-8H,2-6,9-17H2,1H3,(H,19,20)/b8-7+
InChIKey UWHZIFQPPBDJPM-BQYQJAHWBK
ChEBI 28727
性质
化学式 C18H34O2
摩尔质量 282.461 g/mol g·mol⁻¹
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

异油酸与健康

编辑

虽说异油酸是一种反式脂肪酸,但是这种天然反式脂肪可以降低人类血液里面的低密度胆固醇甘油三酯。这正好与其它反式脂肪的作用相反。食用异油酸的人可以减少发生动脉硬化心脏病的发病率。[1] 异油酸也是人奶中的主要反式脂肪。 [2][3]在哺乳动物体内,细胞会把异油酸转化成一种共轭亚油酸[4][5] 共轭亚油酸可以抑制致癌物质的活性。[6]

参考文献

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  1. ^ Natural trans fats may be good for you.页面存档备份,存于互联网档案馆) May 19, 2008(英文)
  2. ^ Precht, D and J.Molkentin C18:1, C18:2, and C8:3 trans and cis fatty acid isomers including conjugated cis delta 9, trans delta 11 linoleic acid (CLA) as well as total fat composition of German human milk lipids, Nahrung 1999 43(4) 233-244(英文)
  3. ^ Friesen, R, and S.M. Innis, Trans Fatty acids in Human milk in Canada declined with the introduction of trans fat food labeling, J. Nut 2006, 136 2558-2561(英文)
  4. ^ Bauman, Dale. cis-9, trans-11 CLA - A Potent Anticarcinogen Found in Milk Fat. [2007-01-15]. (原始内容存档于2006-09-07) (英语). 
  5. ^ Banni S, Angioni E, Murru E, Carta G, Melis M, Bauman D, Dong Y, Ip C. Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland. Nutr Cancer. 2001, 41 (1–2): 91–7. PMID 12094634. doi:10.1207/S15327914NC41-1&2_12. 
  6. ^ Lock AL, Corl BA, Barbano DM, Bauman DE, Ip C. The anticarcinogenic effect of trans-11 18:1 is dependent on its conversion to cis-9, trans-11 CLA by delta9-desaturase in rats. J Nutr. October 1, 2004, 134 (10): 2698–704 [2007-01-15]. PMID 15465769. (原始内容存档于2007-03-17).