1-雄酮(英语:1-Androsterone1-andro,也被称为1-脱氢表雄酮,1-dehydroepiandrosterone,1-DHEAδ1-epiandrosterone,或5α-雄甾-1-烯-3β-醇-17-酮,5α-androst-1-en-3β-ol-17-one)是一种人工合成的同化类固醇(AAS)药物[1]。它可看做是1-睾酮(双氢勃地酮,dihydroboldenone)、1-雄烯二酮以及其它1-脱氢雄激素激素原[1]。它是脱氢表雄酮(DHEA; 5-dehydroepiandrosterone)的双键位置异构体

1-雄酮
临床资料
其他名称1-Andro; 1-Dehydroepiandrosterone; 1-DHEA; δ1-Epiandrosterone; 1-Prasterone; 5α-Androst-1-en-3β-ol-17-one
给药途径口服给药
识别信息
  • (3R,5S,8R,9S,10R,13S,14S)-3-Hydroxy-10,13-dimethyl-3,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
CAS号23633-63-8
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C19H28O2
摩尔质量288.43 g·mol−1
3D模型(JSmol英语JSmol
  • C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC[C@@H]4[C@@]3(C=C[C@@H](C4)O)C
  • InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,12-16,20H,3-6,8,10-11H2,1-2H3/t12-,13-,14-,15-,16-,18-,19-/m0/s1
  • Key:DYMROBVXGSLPAY-LUJOEAJASA-N

另见

编辑

参考文献

编辑
  1. ^ 1.0 1.1 Parr MK, Opfermann G, Geyer H, Westphal F, Sönnichsen FD, Zapp J, Kwiatkowska D, Schänzer W. Seized designer supplement named "1-Androsterone": identification as 3β-hydroxy-5α-androst-1-en-17-one and its urinary elimination. Steroids. 2011, 76 (6): 540–7. PMID 21310167. doi:10.1016/j.steroids.2011.02.001.