HT22细胞是一种来自于小鼠海马体神经元细胞系,由HT4细胞衍生而来[1],常用于构建体外神经元损伤模型[2],如谷氨酸诱导模型[3]过氧化氢诱导模型等[4]

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  1. ^ Davis, JB; Maher, P. Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell line.. Brain research. 1994-07-25, 652 (1): 169–73. PMID 7953717. doi:10.1016/0006-8993(94)90334-4. 
  2. ^ Liu, J; Li, L; Suo, WZ. HT22 hippocampal neuronal cell line possesses functional cholinergic properties.. Life sciences. 2009-02-27, 84 (9-10): 267–71. PMID 19135458. doi:10.1016/j.lfs.2008.12.008. 
  3. ^ Li, Y; Maher, P; Schubert, D. A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion.. Neuron. 1997-08, 19 (2): 453–63. PMID 9292733. doi:10.1016/s0896-6273(00)80953-8. 
  4. ^ Woo, J; Han, D; Park, J; Kim, SJ; Kim, Y. In-depth characterization of the secretome of mouse CNS cell lines by LC-MS/MS without prefractionation.. Proteomics. 2015-11, 15 (21): 3617–22. PMID 26227174. doi:10.1002/pmic.201400623. 

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