散亂蛋白(英語:DishevelledDsh)是涉及鈣離子與非鈣離子Wnt信號通路蛋白質家族。Dsh是一種胞漿內磷酸化蛋白,作為捲曲受體的下游信號分子[1]。其得名於在果蠅中最初發現該基因時,其基因突變會導致身體和翅膀的剛毛定位錯誤[2]

Dishevelled specific domain
鑑定
標誌Dishevelled
PfamPF02377舊版
InterPro英語InterProIPR003351
PROSITE英語PROSITEPDOC50841

參考文獻

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  1. ^ Penton A, Wodarz A, Nusse R. A mutational analysis of dishevelled in Drosophila defines novel domains in the dishevelled protein as well as novel suppressing alleles of axin. Genetics. June 2002, 161 (2): 747–62. PMC 1462152 . PMID 12072470. 
  2. ^ Wallingford JB, Habas R. The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development. October 2005, 132 (20): 4421–36. PMID 16192308. doi:10.1242/dev.02068. 

外部連結

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