水迷宮
水迷宮(water maze),是一種用來測驗動物記憶的實驗設備,其中的路徑充滿了水,使動物具有逃脫的動機 。[1]
存在許多不同的水迷宮,如T-和Y-迷宮、辛辛那提水迷宮和放射臂迷宮。[2][3][4]水迷宮被用來測試辨別學習和空間學習能力。莫里斯水航行任務通常也稱作一個「水迷宮任務」,但是嚴格地說,它並不是一個迷宮。這些迷宮輔助研究的發展,例如海馬突觸可塑性、NMDA受體功能和研究神經退化性疾病,如阿爾茨海默氏症。
參考文獻
編輯- ^ Schenk, Françoise. 5: The Morris Water Maze (is not a maze). Foreman, Nigel; Gillett, Raphael (編). Handbook of Spatial Research Paradigms and Methodologies. Volume 2: Clinical and Comparative Studies. East Sussex, United Kingdom: Psychology Press. 1998: 145–188 [2017-11-30]. ISBN 978-0-86377-807-0. (原始內容存檔於2017-12-01).
- ^ Inheritance of discrimination learning ability and retention in BA and DBA mice. Behavior Genetics. March 1981, 11 (2): 173–177. PMID 7271683. doi:10.1007/BF01065628.
- ^ Vorhees, Charles V.; Williams, Michael T. Cincinnati water maze: A review of the development, methods, and evidence as a test of egocentric learning and memory. Neurotoxicology and Teratology: 1–19. PMC 5056837 . PMID 27545092. doi:10.1016/j.ntt.2016.08.002.
- ^ Water version of the radial-arm maze: learning in three inbred strains of mice. Brain Research. March 1998, 785 (2): 236–244 [2014-05-23]. PMID 9518631. doi:10.1016/S0006-8993(97)01417-0.