二甲啡烷

化合物

二甲啡烷(英語:Dimemorfandimemorphan,全稱3,17-二甲基嗎啡烷3,17-dimethylmorphinan,商品名AstominDastosirrTusben)分子式C18H25N,是一種嗎啡喃衍生物,可用作止咳藥[1][2][3][4]

二甲啡烷
臨床資料
商品名英語Drug nomenclatureAstomin, Datosin, Gentus
AHFS/Drugs.com國際藥品名稱
ATC碼
識別資訊
  • (4bS,8aS,9S)-3,11-Dimethyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene
CAS號36309-01-0  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.048.134 編輯維基數據鏈接
化學資訊
化學式C18H25N
摩爾質量255.41 g·mol−1
3D模型(JSmol英語JSmol
  • CC1=CC2=C(C[C@@H]3N(CC[C@@]42CCCC[C@H]34)C)C=C1
  • InChI=1S/C18H25N/c1-13-6-7-14-12-17-15-5-3-4-8-18(15,16(14)11-13)9-10-19(17)2/h6-7,11,15,17H,3-5,8-10,12H2,1-2H3/t15-,17+,18+/m1/s1 checkY
  • Key:KBEZZLAAKIIPFK-NJAFHUGGSA-N checkY

參考文獻

編輯
  1. ^ Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 427–. ISBN 978-1-4757-2085-3. 
  2. ^ Bruera E, Higginson I, von Gunten CF, Morita T. Textbook of Palliative Medicine and Supportive Care, Second Edition. CRC Press. 15 January 2015: 677–. ISBN 978-1-4441-3526-8. 
  3. ^ Ida H. The nonnarcotic antitussive drug dimemorfan: a review. Clinical Therapeutics. 1997, 19 (2): 215–31. PMID 9152562. doi:10.1016/S0149-2918(97)80111-7. 
  4. ^ Armstrong LL, Goldman MP. Lexi-Comp's Drug Information Handbook International: With Canadian and International Drug Monographs. Lexi-Comp. 1 January 2005. ISBN 978-1-59195-110-0. 

外部連結

編輯