長春西汀

化合物

長春西汀(英語:Vinpocetine 或 ethyl apovincaminate)是一種有機化合物,化學式為C22H26N2O2,屬於長春花生物鹼,存在於小蔓長春花(學名:Vinca minor)的[2]

長春西汀
臨床資料
AHFS/Drugs.com國際藥品名稱
懷孕分級
  • Not recommended
給藥途徑Oral, intravenous
ATC碼
法律規範狀態
法律規範
  • Rx-only[來源請求]
  • Unapproved "New Drug" (as defined by 21 U.S. Code § 321(p)(1)). Use in dietary supplements, food, or medicine is unlawful; otherwise uncontrolled. [1]
藥物動力學數據
生物利用度56.6 ± 8.9%
藥物代謝hepatic
生物半衰期2.54 ± 0.48 hours
排泄途徑renal
識別資訊
  • (3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester
CAS號42971-09-5  ☒N
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.050.917 編輯維基數據鏈接
化學資訊
化學式C22H26N2O2
摩爾質量350.46 g·mol−1
3D模型(JSmol英語JSmol
  • O=C(OCC)C=4n1c3c(c2ccccc12)CCN5[C@H]3[C@](C=4)(CCC5)CC
  • InChI=1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1 checkY
  • Key:DDNCQMVWWZOMLN-IRLDBZIGSA-N checkY

參考文獻

編輯
  1. ^ Vinpocetine in Dietary Supplements. FDA. February 22, 2023 [June 9, 2023]. (原始內容存檔於2024-02-04). 
  2. ^ Zhang YS, Li JD, Yan C. An update on vinpocetine: New discoveries and clinical implications. European Journal of Pharmacology. January 2018, 819: 30–34. PMID 29183836. doi:10.1016/j.ejphar.2017.11.041.