4-溴苯甲醯氯

化合物

4-溴苯甲醯氯是一種有機化合物,化學式為C7H4BrClO,它是苯甲醯氯苯環對位的氫被溴取代的化合物。它可由4-溴苯甲酸草醯氯二甲基甲醯胺的催化下於二氯甲烷中反應得到[1],醯氯化試劑也可使用氯化亞碸[2]。它和苯胺三乙胺的存在下於四氫呋喃中反應,可以得到N-苯基-4-溴苯甲醯胺。[3]

4-溴苯甲醯氯
別名 對溴苯甲醯氯
識別
CAS號 586-75-4  checkY
PubChem 68515
性質
化學式 C7H4BrClO
摩爾質量 219.46 g·mol−1
熔點 42 °C(315 K)
沸點 246 °C(519 K)
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考文獻

編輯
  1. ^ Kay Ahn, Markus Boehm, Matthew F. Brown, Jessica Calloway, Ye Che, Jinshan Chen, Kimberly F. Fennell, Kieran F. Geoghegan, Adam M. Gilbert, Jemy A. Gutierrez, Amit S. Kalgutkar, Adhiraj Lanba, Chris Limberakis, Thomas V. Magee, Inish O』Doherty, Robert Oliver, Brandon Pabst, Jayvardhan Pandit, Kevin Parris, Jeffrey A. Pfefferkorn, Timothy P. Rolph, Rushi Patel, Brandon Schuff, Veerabahu Shanmugasundaram, Jeremy T. Starr, Alison H. Varghese, Nicholas B. Vera, Cecile Vernochet, Jiangli Yan. Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. ACS Chemical Biology. 2016-09-16, 11 (9): 2529–2540 [2021-09-20]. ISSN 1554-8929. doi:10.1021/acschembio.6b00266 (英語). 
  2. ^ Hugo Gallardo, Rodrigo Cristiano, André Vieira, Ricardo Neves Filho, Rajendra Srivastava. Sonogashira Coupling Applied in the Synthesis of 1,2,4-Oxadiazole-Based Nonsymmetrical Liquid Crystals. Synthesis. 2008-02, 2008 (4): 605–609 [2021-09-20]. ISSN 0039-7881. doi:10.1055/s-2008-1032156. (原始內容存檔於2018-06-03) (英語). 
  3. ^ Clarice A. D. Caiuby, Matheus P. de Jesus, Antonio C. B. Burtoloso. α-Imino Iridium Carbenes from Imidoyl Sulfoxonium Ylides: Application in the One-Step Synthesis of Indoles. The Journal of Organic Chemistry. 2020-06-05, 85 (11): 7433–7445 [2021-09-20]. ISSN 0022-3263. doi:10.1021/acs.joc.0c00833. (原始內容存檔於2021-11-07) (英語).