2-羟基苄胺

化合物

2-羟基苄胺是一种有机化合物,化学式为C7H9NO。它可由碘化亚钐还原2-羟基苯甲腈制得。[1]碳酸钠存在下,它和氯乙酰氯反应,可以得到N-(2-羟基苄基)氯乙酰胺。[2]它和二硫化碳DMSO中反应,可以得到3,4-二氢-2H-1,3-苯并𫫇嗪-2-硫酮()。[3]

2-HOBA
识别信息
  • 2-(aminomethyl)phenol
CAS号932-30-9  checkY
PubChem CID
ECHA InfoCard100.012.045 编辑维基数据链接
化学信息
化学式C7H9NO
摩尔质量123.16 g·mol−1
3D模型(JSmol英语JSmol
  • C1=CC=C(C(=C1)CN)O
  • InChI=1S/C7H9NO/c8-5-6-3-1-2-4-7(6)9/h1-4,9H,5,8H2
  • Key:KPRZOPQOBJRYSW-UHFFFAOYSA-N

参考文献

编辑
  1. ^ Gary A. Molander. John Wiley & Sons, Inc. , 编. Reductions with Samarium(II) Iodide. Hoboken, NJ, USA: John Wiley & Sons, Inc. 1994-10-27: 211–367 [2021-12-10]. ISBN 9780471264187. doi:10.1002/0471264180.or046.03. (原始内容存档于2022-02-27) (英语). 
  2. ^ Quinn P. Peterson, Danny C. Hsu, David R. Goode, Chris J. Novotny, Ryan K. Totten, Paul J. Hergenrother. Procaspase-3 Activation as an Anti-Cancer Strategy: Structure−Activity Relationship of Procaspase-Activating Compound 1 (PAC-1) and Its Cellular Co-Localization with Caspase-3. Journal of Medicinal Chemistry. 2009-09-24, 52 (18): 5721–5731 [2021-12-10]. ISSN 0022-2623. PMC 2749958 . PMID 19708658. doi:10.1021/jm900722z. (原始内容存档于2021-12-03) (英语). 
  3. ^ Chaochao Ding, Shaoli Wang, Yaoguang Sheng, Qian Dai, Yunjie Zhao, Guang Liang, Zengqiang Song. One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence. RSC Advances. 2019, 9 (46): 26768–26772 [2021-12-10]. ISSN 2046-2069. doi:10.1039/C9RA04540F (英语).