TAS2R45
位於12號人類染色體的基因
味覺感受器，類型2，成員45，TAS2R45 是一個人類基因組中TAS2R45基因編碼的蛋白質，是苦味味覺感受器的一員。[1][2]
| 味覺感受器，類型2，成員45 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 標識 | |||||||||||||
| 代號 | TAS2R45; GPR59; T2R45; ZG24P | ||||||||||||
| 擴展標識 | 遺傳學：613967 GeneCards: TAS2R45 Gene | ||||||||||||
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| 直系同源體 | |||||||||||||
| 物種 | 人類 | 小鼠 | |||||||||||
| Entrez | 259291 | n/a | |||||||||||
| Ensembl | ENSG00000256436 | n/a | |||||||||||
| UniProt | P59539 | n/a | |||||||||||
| mRNA序列 | NM_176886 | n/a | |||||||||||
| 蛋白序列 | NP_795367 | n/a | |||||||||||
| 基因位置 |
Chr 12: 11.18 – 11.18 Mb | n/a | |||||||||||
| PubMed查詢 | [1] | n/a | |||||||||||
另見 編輯
參考文獻 編輯
- ^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W. The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides. Nat Genet. Oct 2002, 32 (3): 397–401. PMID 12379855. doi:10.1038/ng1014.
- ^ Entrez Gene: TAS2R45 taste receptor, type 2, member 45.
拓展閱讀 編輯
- Margolskee RF. Molecular mechanisms of bitter and sweet taste transduction.. J. Biol. Chem. 2002, 277 (1): 1–4. PMID 11696554. doi:10.1074/jbc.R100054200.
- Montmayeur JP, Matsunami H. Receptors for bitter and sweet taste.. Curr. Opin. Neurobiol. 2002, 12 (4): 366–71. PMID 12139982. doi:10.1016/S0959-4388(02)00345-8.
- Strausberg RL, Feingold EA, Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Zhang Y, Hoon MA, Chandrashekar J; et al. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.. Cell. 2003, 112 (3): 293–301. PMID 12581520. doi:10.1016/S0092-8674(03)00071-0.
- Go Y, Satta Y, Takenaka O, Takahata N. Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.. Genetics. 2006, 170 (1): 313–26. PMC 1449719 . PMID 15744053. doi:10.1534/genetics.104.037523.
