MASP-2
位於1號人類染色體的基因
甘露糖结合凝集素丝氨酸蛋白酶2 （Mannan-binding lectin serine protease 2，也被称为 甘露糖相关丝氨酸蛋白酶2，mannose-associated serine protease 2，缩写MASP-2）是由人类基因 MASP2 编码的一种酶。[1][2][3]
| Mannan-binding lectin serine peptidase 2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 PDB rendering based on 1q3x. | |||||||||||||
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| 标识 | |||||||||||||
| 代号 | MASP2; MAP19; MASP-2; MASP1P1; sMAP | ||||||||||||
| 扩展标识 | 遗传学：605102 鼠基因：1330832 同源基因：4819 GeneCards: MASP2 Gene | ||||||||||||
| EC編號 | 3.4.21.104 | ||||||||||||
| 直系同源体 | |||||||||||||
| 物种 | 人类 | 小鼠 | |||||||||||
| Entrez | 10747 | 17175 | |||||||||||
| Ensembl | ENSG00000009724 | ENSMUSG00000028979 | |||||||||||
| UniProt | O00187 | Q91WP0 | |||||||||||
| mRNA序列 | NM_006610 | NM_001003893 | |||||||||||
| 蛋白序列 | NP_006601 | NP_001003893 | |||||||||||
| 基因位置 |
Chr 1: 11.03 – 11.05 Mb |
Chr 4: 148.6 – 148.62 Mb | |||||||||||
| PubMed查询 | [1] | [2] | |||||||||||
另见 编辑
参考文献 编辑
- ^ Entrez Gene: mannan-binding lectin serine peptidase 2. （原始内容存档于2019-10-18）.
- ^ A second serine protease associated with mannan-binding lectin that activates complement. Nature. April 1997, 386 (6624): 506–10. Bibcode:1997Natur.386..506T. PMID 9087411. doi:10.1038/386506a0.
- ^ MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway. Immunobiology. August 1998, 199 (2): 348–57. PMID 9777418. doi:10.1016/S0171-2985(98)80039-9.