MASP-2

Mannan-binding lectin serine peptidase 2
Mannan-binding lectin serine peptidase 2
	PDB rendering based on 1q3x.
有效结构
PDB	直系同源检索：PDBe, RCSB
PDB查询代码列表
	1Q3X, 1SZB, 1ZJK, 3TVJ, 4FXG
标识
代号	MASP2; MAP19; MASP-2; MASP1P1; sMAP
扩展标识	遗传学：605102 鼠基因：1330832 同源基因：4819 GeneCards: MASP2 Gene
EC编号	3.4.21.104
基因本体论描述
分子功能	· complement component C4b binding; · serine-type endopeptidase activity; · calcium ion binding; · protein binding; · peptidase activity; · calcium-dependent protein binding;
细胞成分	· extracellular region; · extracellular exosome;
生物过程	· complement activation, lectin pathway; · proteolysis; · complement activation; · complement activation, classical pathway; · innate immune response;
	Sources: Amigo / QuickGO
直系同源体
物种	人类
Entrez	10747
Ensembl	ENSG00000009724
UniProt	O00187
mRNA序列	NM_006610
蛋白序列	NP_006601
基因位置	Chr 1:; 11.03 – 11.05 Mb
PubMed查询	[1]
	查; 论; 编;

甘露糖结合凝集素丝氨酸蛋白酶2 （Mannan-binding lectin serine protease 2，也被称为 甘露糖相关丝氨酸蛋白酶2，mannose-associated serine protease 2，缩写MASP-2）是由人类基因 MASP2 编码的一种酶。^[1]^[2]^[3]

另见

甘露聚糖结合凝集素

参考文献

^ Entrez Gene: mannan-binding lectin serine peptidase 2. （原始内容存档于2019-10-18）.
^ A second serine protease associated with mannan-binding lectin that activates complement. Nature. April 1997, 386 (6624): 506–10. Bibcode:1997Natur.386..506T. PMID 9087411. doi:10.1038/386506a0.
^ MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway. Immunobiology. August 1998, 199 (2): 348–57. PMID 9777418. doi:10.1016/S0171-2985(98)80039-9.

外部链接

医学主题词表（MeSH）：MASP+Proteases

MASP-2引用了美国国家医学图书馆提供的资料，这些资料属于公共领域。

[entrez-1] Entrez Gene: mannan-binding lectin serine peptidase 2. （原始内容存档于2019-10-18）.

[pmid9087411-2] A second serine protease associated with mannan-binding lectin that activates complement. Nature. April 1997, 386 (6624): 506–10. Bibcode:1997Natur.386..506T. PMID 9087411. doi:10.1038/386506a0.

[pmid9777418-3] MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway. Immunobiology. August 1998, 199 (2): 348–57. PMID 9777418. doi:10.1016/S0171-2985(98)80039-9.

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