MASP-2

Mannan-binding lectin serine peptidase 2
Mannan-binding lectin serine peptidase 2
	PDB rendering based on 1q3x.
有效結構
PDB	直系同源檢索：PDBe, RCSB
PDB查詢代碼列表
	1Q3X, 1SZB, 1ZJK, 3TVJ, 4FXG
標識
代號	MASP2; MAP19; MASP-2; MASP1P1; sMAP
擴展標識	遺傳學：605102 鼠基因：1330832 同源基因：4819 GeneCards: MASP2 Gene
EC編號	3.4.21.104
基因本體論描述
分子功能	· complement component C4b binding; · serine-type endopeptidase activity; · calcium ion binding; · protein binding; · peptidase activity; · calcium-dependent protein binding;
細胞成分	· extracellular region; · extracellular exosome;
生物過程	· complement activation, lectin pathway; · proteolysis; · complement activation; · complement activation, classical pathway; · innate immune response;
	Sources: Amigo / QuickGO
直系同源體
物種	人類
Entrez	10747
Ensembl	ENSG00000009724
UniProt	O00187
mRNA序列	NM_006610
蛋白序列	NP_006601
基因位置	Chr 1:; 11.03 – 11.05 Mb
PubMed查詢	[1]
	閱; 論; 編;

甘露糖結合凝集素絲氨酸蛋白酶2 （Mannan-binding lectin serine protease 2，也被稱為 甘露糖相關絲氨酸蛋白酶2，mannose-associated serine protease 2，縮寫MASP-2）是由人類基因 MASP2 編碼的一種酶。^[1]^[2]^[3]

另見

甘露聚糖結合凝集素

參考文獻

^ Entrez Gene: mannan-binding lectin serine peptidase 2. （原始內容存檔於2019-10-18）.
^ A second serine protease associated with mannan-binding lectin that activates complement. Nature. April 1997, 386 (6624): 506–10. Bibcode:1997Natur.386..506T. PMID 9087411. doi:10.1038/386506a0.
^ MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway. Immunobiology. August 1998, 199 (2): 348–57. PMID 9777418. doi:10.1016/S0171-2985(98)80039-9.

外部連結

醫學主題詞表（MeSH）：MASP+Proteases

MASP-2引用了美國國家醫學圖書館提供的資料，這些資料屬於公共領域。

[entrez-1] Entrez Gene: mannan-binding lectin serine peptidase 2. （原始內容存檔於2019-10-18）.

[pmid9087411-2] A second serine protease associated with mannan-binding lectin that activates complement. Nature. April 1997, 386 (6624): 506–10. Bibcode:1997Natur.386..506T. PMID 9087411. doi:10.1038/386506a0.

[pmid9777418-3] MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway. Immunobiology. August 1998, 199 (2): 348–57. PMID 9777418. doi:10.1016/S0171-2985(98)80039-9.

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