NEUROD1

NEUROD1
已知的结构
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	2QL2
识别号
别名	NEUROD1；, BETA2, BHF-1, MODY6, NEUROD, bHLHa3, neuronal differentiation 1, T2D
外部ID	OMIM：601724 MGI：1339708 HomoloGene：1871 GeneCards：NEUROD1
基因位置（人类）
染色体	2号染色体
终止	181,680,827 bp
基因位置（小鼠）
染色体	小鼠2号染色体
终止	79,287,095 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• sequence-specific DNA binding; • 转录共激活因子活性; • DNA结合; • protein dimerization activity; • DNA结合转录因子活性; • DNA-binding transcription activator activity, RNA polymerase II-specific; • 转录因子结合; • chromatin binding; • RNA polymerase II cis-regulatory region sequence-specific DNA binding; • E-box binding; • 血浆蛋白结合; • protein heterodimerization activity; • double-stranded DNA binding; • DNA-binding transcription factor activity, RNA polymerase II-specific;
细胞组分	• 细胞质; • 胞内; • 核质; • RNA polymerase II transcription regulator complex; • 细胞核;
生物学过程	• positive regulation of transcription regulatory region DNA binding; • regulation of neuron differentiation; • 神经发生; • 细胞分化; • cell fate commitment; • regulation of transcription, DNA-templated; • pancreatic PP cell fate commitment; • glucose homeostasis; • regulation of insulin secretion; • enteroendocrine cell differentiation; • dentate gyrus development; • signal transduction involved in regulation of gene expression; • neuron development; • insulin secretion; • positive regulation of DNA-binding transcription factor activity; • response to glucose; • transcription by RNA polymerase II; • embryonic organ morphogenesis; • cerebellum development; • transcription, DNA-templated; • 神经系统的发育; • positive regulation of transcription, DNA-templated; • multicellular organism development; • hindbrain development; • nucleocytoplasmic transport; • positive regulation of neuron differentiation; • positive regulation of cell differentiation; • nitric oxide mediated signal transduction; • positive regulation of apoptotic process; • regulation of intestinal epithelial structure maintenance; • 内耳的发生; • camera-type eye development; • pancreatic A cell fate commitment; • amacrine cell differentiation; • negative regulation of type B pancreatic cell apoptotic process; • cellular response to glucose stimulus; • anterior/posterior pattern specification; • endocrine pancreas development; • positive regulation of transcription by RNA polymerase II; • negative regulation of receptor signaling pathway via JAK-STAT;
	Sources:Amigo / QuickGO
直系同源
	4760
	18012
	ENSG00000162992
	ENSMUSG00000034701
	Q13562
	Q60867
	NM_002500
	NM_010894
	NP_002491
	NP_035024
	维基数据
查看/编辑人类	查看/编辑小鼠